Nothing is known about Melissa's life prior to or as the outbreak began, except that she had a sister, Mercy, parents and could have lived in or near Woodbury.
After the Church group blew the gates to Woodbury, and attracted a horde of walkers, this girl tried escaping with her family, but were pinned down by walkers. She was the only survivor, and was later rescued by the remaining Woodbury survivors.
Melissa starts having skin infections after settling in to the sewers with rest of the survivors.
- Melissa is most likely an error and mixed with the character of Mercy Slocum.