Biehn was born in Anniston, Alabama, the second of three boys born to Marcia (née Connell) and Don Biehn, a lawyer. He is of German descent on his father's side and Irish on his mother's side. When he was young, he moved with his family to Lincoln, Nebraska, and then to Lake Havasu City, Arizona, where he was a member of the high school drama club before graduating. He attended the drama program at the University of Arizona, where he was a member of the Sigma Nu fraternity before moving to Hollywood.
- The Fan
- The Terminator
- The Abyss
- Terminator 2: Judgment Day
- The Rock
- Megiddo: The Omega Code 2
- He's one of six The Walking Dead cast members to have appeared in the Terminator franchise. The others being Xander Berkeley (Gregory), Kerry Cahill (Dianne), Joshua Mikel (Jared), Zach McGowan (Justin) and Robert Patrick (Mays/Mays' Twin).
- Additionally, Gale Anne Hurd is a producer in the franchise.