The state of Mississippi was the 32nd most populous and 32nd largest state in America before the outbreak
Nothing is known about Mississippi during the outbreak. It can be assumed that during the initial stages of the walker epidemic, it followed the example of California, with state and local police being among the first responders, with these first responders being joined by military units if and when a state of emergency was declared, or when Operation Cobalt was put into effect.
Morgan arrives in Mississippi by accident, after falling asleep in the back of a truck while taking shelter from a storm in Texas. When he wakes up, he finds himself at a truck stop and comes across two survivors, Wendell and his sister Sarah, where they have several trucks loaded with supplies that they deliver to various locations for survivors.